May 1, 1994Clinical Science

Analysis of Vagal Effects on Ventricular Rhythm in Patients with Atrial Fibrillation

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Why the study?

Does methylatropine alter ventricular rhythm parameters in patients with chronic atrial fibrillation?

Structured PICO

Does methylatropine alter ventricular rhythm parameters in patients with chronic atrial fibrillation?

Population

16 patients with chronic atrial fibrillation

Intervention

Methylatropine (0.02 mg/kg intravenously)

Comparator

Baseline ventricular rhythm after administration of propranolol (0.2 mg/kg intravenously)

Outcome

Ventricular rhythm parameters (mean, shortest, and longest R-R intervals, ratio of longest to shortest R-R interval, and coefficient of variation of R-R intervals)surrogate

Vagal stimulation lowers ventricular rate during atrial fibrillation by directly affecting the atrioventricular node and augmenting concealed conduction.

Discussion

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Implication

Confirms vagal slowing of ventricular rate in chronic AF; leaves open therapeutic role of anticholinergics.

Cite This Study

Berg et al. (1994) studied this question.

synapsesocial.com/papers/6a87b5373f31f6b699bb5332 https://doi.org/10.1042/cs0860531

Topics

Atrial fibrillation Persistent AF management Anticoagulation in AF

View Full Paper

Ask AI

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Analysis of Vagal Effects on Ventricular Rhythm in Patients with Atrial Fibrillation

Structured PICO

Discussion

Implication

Cite This Study

Topics

Analysis of Vagal Effects on Ventricular Rhythm in Patients with Atrial Fibrillation

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Topics

Also Consider