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The use of three-dimensional (3D) bio-scaffolds for bone regeneration has gained significant attention due to the increasing demand for effective bone graft substitutes. Among various bioceramics, bredigite (Ca7MgSi4O16) has emerged as a promising candidate due to its excellent bioactivity, suitable mechanical properties, and controlled biodegradability. Recent advancements in 3D printing technologies have enabled the fabrication of porous bredigite-based scaffolds with tunable structural and biological characteristics, facilitating enhanced cell adhesion, proliferation, and osteogenic differentiation. This review provides a comprehensive analysis of the latest developments in bredigite-based 3D-printed scaffolds, focusing on their fabrication techniques, mechanical behavior, and potential biomedical applications. Additionally, the key future directions for optimizing these scaffolds are discussed.
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Sharifjafari et al. (2024) studied this question.
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