Why the study?
The study was conducted to evaluate long-term changes in systolic and diastolic cardiac functions using tissue Doppler imaging in children with sickle cell anemia.
Serial tissue Doppler imaging demonstrates progressive worsening of global systolic and diastolic functions over time in children with sickle cell anemia.
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May support serial tissue Doppler monitoring in pediatric sickle cell anemia; leaves open need for prospective validation before practice change.
Giray et al. (2022) studied this question.
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