Why the study?
Does deficiency in angiotensin AT1a receptors prevent diabetes-induced hypertension in mice?
Does deficiency in angiotensin AT1a receptors prevent diabetes-induced hypertension in mice?
Angiotensin AT1a receptors play a critical role in mediating diabetes-induced hypertension and cardiac autonomic responses in a mouse model.
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AT1a deficiency prevents diabetes-induced hypertension in mice; leaves open translation to human therapy.
Wichi et al. (2006) studied this question.
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