Multimodality imaging, including SPECT, can accurately diagnose apical hypertrophic cardiomyopathy and safely exclude acute coronary syndrome, avoiding the need for invasive coronary angiography.
Imaging aids apical HCM diagnosis amid criteria variability; leaves open prospective validation before guideline adoption.
Apical hypertrophic cardiomyopathy is rare familial form of hypertrophic cardiomyopathy, with hypertrophy mainly affecting the apex of the left ventricle and characterized by a spade-like left ventricular cavity. Despite varying presentation, impaired capabilities of some standard instrumental methods and dissent on diagnostic criteria several diagnostic characteristics estimated by various noninvasive imaging modalities make it possible to establish a diagnosis with high accuracy. We hereby describe a case with electrocardiographic abnormalities and chest pain with suspected acute coronary syndrome. Acute coronary syndrome was excluded as well as performing invasive coronary angiography was avoided using advanced diagnostic tools including single photon emission computed tomography and apical hypertrophic cardiomyopathy was demonstrated by careful differential diagnosis.
No takes yet. Share an insight, caveat, or question.
Chanakhchian et al. (2023) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: