Why the study?
Foot-and-mouth disease virus causes devastating disease in cloven-hoofed animals, and neutralizing antibodies play critical roles in viral defense.
Structural analysis of FMDV with bovine neutralizing antibodies reveals determinants of cross-neutralization.
Foot-and-mouth disease virus (FMDV) causes a highly contagious and economically devastating disease in cloven-hoofed animals, and neutralizing antibodies play critical roles in the defense against viral infections. Here, we isolated a bovine antibody (R55) using the single B cell antibody isolation technique.
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A 2021 study studied this question.
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