Why the study?
Does IPOP-MRI with ECG gating accurately evaluate lipomatous metaplasia compared to black-blood T1-weighted imaging in patients with old myocardial infarction?
Does IPOP-MRI with ECG gating accurately evaluate lipomatous metaplasia compared to black-blood T1-weighted imaging in patients with old myocardial infarction?
IPOP-MRI with ECG gating is a viable alternative method for evaluating lipomatous metaplasia in patients with old myocardial infarction, showing good correlation with conventional black-blood T1-weighted imaging.
IPOP-MRI with ECG gating may serve as alternative for lipomatous metaplasia assessment in old MI; extends validation but remains hypothesis-generating.
We present an alternative method for evaluating cardiac fat tissue-dual gradient-echo in-phase and opposed-phase magnetic resonance imaging (IPOP-MRI) with electrocardiographic (ECG) gating. Conventional IPOP-MRI can be used to evaluate small amounts of fat and is widely used for abdominal imaging, but cardiac motion artifacts make its use difficult for cardiac imaging. Using ECG gating prior to IPOP-MRI, we evaluated lipomatous metaplasia after myocardial infarction. The areas of lipomatous metaplasia measured by IPOP-MRI with ECG gating correlated well with those areas on black-blood T(1)-weighted imaging (r=0.82, P<0.0001, mean bias-0.29 cm(2), limit of agreement+/-2.06 cm(2)).
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Okayama et al. (2010) studied this question.