Why the study?
Echocardiographic myocardial strain imaging is recommended in adult cancer patients, but its role in pediatric childhood cancer survivors has not been well established.
Does echocardiographic myocardial strain imaging provide added value in identifying cardiac dysfunction in pediatric survivors of anthracycline-treated childhood cancer compared to controls?
Population
Childhood cancer survivors ≥3 years from last anthracycline treatment and controls
Comparison
Childhood cancer survivors vs controls
Design
Multicenter study
Authors
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Single strain measurements offer limited added value in survivors; leaves open whether serial changes or combined metrics improve risk stratification.
Does echocardiographic myocardial strain imaging provide added value in identifying cardiac dysfunction in pediatric survivors of anthracycline-treated childhood cancer compared to controls?
Single longitudinal strain measurements offer limited added value for identifying pediatric anthracycline-treated cancer survivors at risk for cardiac dysfunction.
Slieker et al. (2019) studied this question.