Population
In vitro protein interaction model (F-actin, filamin1, tropomyosin)
Comparison
Addition of tropomyosin to F-actin vs F-actin and filamin without tropomyosin
Design
Preclinical
Authors
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No immediate clinical implications; leaves open filamin-tropomyosin interactions in non-muscle cytoskeletal regulation for further study.
Tropomyosin inhibits the precipitation of F-actin induced by filamin, suggesting filamin acts on F-actin in non-muscle cells similarly to alpha-actinin.
Maruyama et al. (1978) studied this question.
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