Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
March 20, 2012HepatologyOpen Access

Liver PLTP promotes VLDL production and increases circulating levels of apoB-containing lipoproteins, while also mediating reverse lipopolysaccharide transport.

View Full Paper
Ask AI
Bookmark
Share

Design

Editorial

Authors

LLLaurent Lagrost

Discussion

Loading...

Member takes

Overview

Dual hepatic PLTP effects on atherogenic lipoproteins and LPS transport leave net CV impact unresolved; further studies needed before targeting.

Key Points

Key points are not available for this paper at this time.

Cite This Study

Laurent Lagrost (2012) studied this question.

synapsesocial.com/papers/6a87edd31fec1a0b3d263bbdhttps://doi.org/10.1002/hep.25725
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Genetics and molecular biology: phospholipid transfer protein in atherogenesis2006 · 3 citations
  2. 2Phospholipid Transfer Protein (PLTP) in Cholesterol Handling: Implications for Mitochondrial Lipid Homeostasis in Human iPSC-Derived Cardiomyocytes2026 · 3 citations
  3. 3Plasma phospholipid transfer protein activity, a determinant of HDL kinetics <i>in vivo</i>2006 · 8 citations
  4. 4Phospholipid transfer protein gene knock-out mice have low high density lipoprotein levels, due to hypercatabolism, and accumulate apoA-IV-rich lamellar lipoproteins2000 · 110 citations
  5. 5Acute Elevation of Plasma PLTP Activity Strongly Increases Pre-existing Atherosclerosis2008 · 31 citations