Population
Single cardiac ryanodine receptors (RyRs) in lipid bilayers
Design
Preclinical
Authors
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Submillisecond Ca2+ triggers may govern cardiac EC coupling; leaves open validation in intact myocytes and in vivo models.
Brief submillisecond Ca2+ triggers are adequate to activate the cardiac ryanodine receptor, supporting the local control concept of excitation-contraction coupling.
Zahradnı́ková et al. (1999) studied this question.
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