Why the study?
Does the plasma heparin assay improve anticoagulation monitoring compared to APTT in patients receiving heparin therapy?
Population
Patients receiving heparin therapy in selected clinical situations
Comparison
Plasma heparin assay for monitoring heparin… vs APTT (activated partial thromboplastin time)
Design
Review
Authors
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May guide heparin monitoring in selected cases; leaves open superiority over APTT pending prospective trials.
Does the plasma heparin assay improve anticoagulation monitoring compared to APTT in patients receiving heparin therapy?
This review outlines clinical indications for using the plasma heparin assay over APTT in specific scenarios like heparin resistance or combined anticoagulant therapy, while noting the lack of prospective trial validation.
Marci et al. (1993) studied this question.
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