The characteristic step-like action potential obtained near the AV node in dogs originates from AV node cells or adjacent junctional tissue.
No direct clinical translation from canine models; leaves open validation in human AV nodal electrophysiology.
In the region of the atrioventricular node a characteristic cell potential was obtained by microelectrode recording in dogs. The resting and action potentials obtained here were small and the latter had a step-like potential before the steepest rise. The site of origin was examined histologically by a special staining technic and was found to be from a cell of the atrioventricular node or a part of the special junctional tissue adjacent to it.
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Sano et al. (1959) studied this question.
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