What question did this study set out to answer?

To determine how varying intravascular volume states affect the diagnostic accuracy of pulsus paradoxus and echocardiographic right ventricular diastolic collapse in detecting cardiac tamponade.

November 1, 1985CirculationOpen Access

Effects of intravascular volume state on the value of pulsus paradoxus and right ventricular diastolic collapse in predicting cardiac tamponade.

View Full Paper

Ask AI

Bookmark

Why the study?

Does right ventricular diastolic collapse improve prediction of cardiac tamponade compared to pulsus paradoxus across different intravascular volume states in a canine model?

Population

5 chronically prepared, conscious mongrel dogs during 37 episodes of cardiac tamponade at three different…

Comparison

Right ventricular diastolic collapse detected by… vs Pulsus paradoxus

Design

Preclinical

Authors

TCT L CogswellAtrium Health Wake Forest Baptist GBG A BernathAtrium Health Wake Forest Baptist LWL. Samüel WannCardiac Imaging

Discussion

Member takes

Implication

Caution against clinical adoption; leaves open human validation of RV diastolic collapse for tamponade across volume states.

Key Points

To determine how varying intravascular volume states affect the diagnostic accuracy of pulsus paradoxus and echocardiographic right ventricular diastolic collapse in detecting cardiac tamponade.
Evaluated 5 chronically prepared, conscious mongrel dogs across 37 induced cardiac tamponade episodes.
Adjusted intravascular volume to hypovolemic (-2 to -6 mm Hg), euvolemic (0 to 4 mm Hg), and hypervolemic (6 to 10 mm Hg) mean right atrial pressures.
Continuously measured cardiac output, aortic pressure, right atrial pressure, intrapericardial pressure, and two-dimensional echocardiographic wall motion.
Right ventricular diastolic collapse maintained high sensitivity and specificity for detecting elevated intrapericardial pressure across hypovolemic, euvolemic, and hypervolemic states.
Pulsus paradoxus demonstrated high sensitivity and specificity in hypovolemia, but its diagnostic sensitivity and specificity declined substantially in euvolemic and hypervolemic states.
Right ventricular diastolic collapse was more sensitive and specific than pulsus paradoxus during euvolemia and hypervolemia, while both markers showed equivalent utility in hypovolemia.

Structured PICO

Does right ventricular diastolic collapse improve prediction of cardiac tamponade compared to pulsus paradoxus across different intravascular volume states in a canine model?

Population

5 chronically prepared, conscious mongrel dogs during 37 episodes of cardiac tamponade at three different intravascular volumes (hypovolemic, euvolemic, hypervolemic)

Intervention

Right ventricular diastolic collapse detected by two-dimensional echocardiography

Comparator

Pulsus paradoxus

Outcome

Sensitivity and specificity in predicting increases in intrapericardial pressuresurrogate

Right ventricular diastolic collapse is a more reliable echocardiographic marker for cardiac tamponade than pulsus paradoxus, particularly in euvolemic and hypervolemic states.

Cite This Study

Cogswell et al. (1985) studied this question.

synapsesocial.com/papers/6a87fc94fc0635f4eccf0227 https://doi.org/10.1161/01.cir.72.5.1076

View Full Paper

Ask AI

Bookmark

Effects of intravascular volume state on the value of pulsus paradoxus and right ventricular diastolic collapse in predicting cardiac tamponade.

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Effects of intravascular volume state on the value of pulsus paradoxus and right ventricular diastolic collapse in predicting cardiac tamponade.

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Also Consider