⌘+K

Pulse Explore Clubs Researchers Journals

Home Clubs Explore

August 1, 1981Clinical Chemistry

Radioimmunoassay for plasma thromboxane B2.

View Full Paper

Ask AI

Bookmark

Share

Population

22 normal human subjects and a rabbit model

Comparison

Radioimmunoassay for plasma thromboxane B2… vs Pre- versus post-aspirin ingestion; plasma…

Design

Preclinical

Authors

DMDaisy S. McCannNIHR Southampton Biomedical Research Centre JTJoyce M. Tokarsky RSRichard P. SorkinNova Southeastern University

Discussion

Loading...

Member takes

Implication

Assay provides normative thromboxane B2 data sensitive to aspirin; leaves open clinical validation for platelet monitoring.

Structured PICO

P

Population

22 normal human subjects and a rabbit model

I

Intervention

Radioimmunoassay for plasma thromboxane B2; aspirin ingestion (in humans); intravenous [3H]thromboxane B2 (in rabbits)

C

Comparator

Pre- versus post-aspirin ingestion; plasma versus serum

O

Outcome

Plasma thromboxane B2 concentrationsurrogate

The developed radioimmunoassay for plasma thromboxane B2 is simple, sensitive, and can be used to reflect acute events involving platelet aggregation.

Cite This Study

McCann et al. (1981) studied this question.

synapsesocial.com/papers/6a88000404120b0d52eb3549 https://doi.org/10.1093/clinchem/27.8.1417

View Full Paper

Ask AI

Bookmark

Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1A Rapid Assay for Platelet Thromboxane Production and Its Use in Assessing Prior Aspirin Ingestion1988 · 22 citations
2Estimated rate of thromboxane secretion into the circulation of normal humans.1986 · 236 citations
3Increased thromboxane biosynthesis in patients with acute cerebral ischemia.1993 · 95 citations
4Risk factors for carotid atherosclerosis and platelet activation.1994 · 8 citations
5Plasma 11-dehydrothromboxane B2: a reliable indicator of platelet hyperfunction in patients with ischemic stroke1991 · 11 citations