January 1, 2012The Korean Journal of Internal MedicineOpen Access

Plasma N-Terminal Pro-B-Type Natriuretic Peptide Is Predictive of Perioperative Cardiac Events in Patients Undergoing Vascular Surgery

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Why the study?

Does preoperative measurement of NT-proBNP predict perioperative cardiac events in patients undergoing non-cardiac vascular surgery?

Population

365 patients scheduled for non-cardiac vascular surgery, mean age 67 years, 91% males.

Comparison

Preoperative measurement of plasma N-terminal… vs Modified Revised Cardiac Risk Index and stress…

Design

Cohort

Follow-up

5 days after surgery

Authors

JYJi Hyun YangSamsung Medical Center JCJin Ho ChoiSeoul National University YKYoung-Wook Ki

Discussion

Member takes

Implication

Supports preoperative NT-proBNP for risk stratification in vascular surgery; leaves open prospective validation of outcome improvement.

Structured PICO

Does preoperative measurement of NT-proBNP predict perioperative cardiac events in patients undergoing non-cardiac vascular surgery?

Population

365 patients scheduled for non-cardiac vascular surgery, mean age 67 years, 91% males.

Intervention

Preoperative measurement of plasma N-terminal pro-B-type natriuretic peptide (NT-proBNP)

Comparator

Modified Revised Cardiac Risk Index (RCRI) and stress thallium scans

Outcome

Composite of acute myocardial infarction, congestive heart failure including acute pulmonary edema, and primary cardiac death within 5 days after surgerycomposite

Preoperative NT-proBNP > 302 pg/mL is a strong independent predictor of perioperative cardiac events in patients undergoing non-cardiac vascular surgery.

Cite This Study

Yang et al. (2012) studied this question.

synapsesocial.com/papers/6a880ac9c0c64b7dddeb36ea https://doi.org/10.3904/kjim.2012.27.3.301

Topics

Heart failure HFrEF treatment

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