Why the study?
Platelet activation plays a central role in converting atherosclerotic cardiovascular disease into major adverse events, motivating evaluation of platelet parameters across the spectrum of ischemic heart disease.
Are platelet volume indices and platelet count correlated with the spectrum of ischemic artery disease (myocardial infarction and unstable angina)?
Population
Patients with myocardial infarction, unstable angina, and healthy controls at a tertiary care hospital
Comparison
Myocardial infarction vs unstable angina vs healthy controls
Authors
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MPV may mark prethrombotic states in CAD; hypothesis-generating and should not yet change practice.
Are platelet volume indices and platelet count correlated with the spectrum of ischemic artery disease (myocardial infarction and unstable angina)?
Larger platelets and increased platelet volume indices are associated with ischemic heart disease and may serve as a marker for prethrombotic states in coronary artery disease.
Gamit et al. (2020) studied this question.
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