Why the study?
Are platelet indices (MPV, PDW, and platelet count) altered in patients with coronary artery disease compared to a normal population?
Are platelet indices (MPV, PDW, and platelet count) altered in patients with coronary artery disease compared to a normal population?
Platelet volume indices (MPV and PDW) are significantly elevated in patients with coronary artery disease, suggesting a potential role in predicting impending CAD events.
Answers are grounded in this paper and cite their sources.
May support platelet indices for CAD risk stratification; hypothesis-generating, requires prospective validation before clinical use.
O bjectives: 1. To investigate platelet indices in patients of Myocardial infarction, Unstable angina, and Stable angina. 2. To compare changes in platelet indices among Patients of myocardial infarction, unstable angina, stable angina and normal population. Material and Methods: This study was carried out in the Department of Medicine, NIMS Medical College and Hospital, Jaipur, Rajasthan. To investigate the values of platelet indices MPV, PDW and platelet count with the view of exploring their use in predicting the possibility of impending events of coronary artery disease on 110 patients admitted in wards an d ICU under Department of Medicine and 110 controls who were the normal during the study period. Results: On comparing patients of coronary artery disease with control group it was found that MPV and PDW were raised and platelet counts decreased with a highly significant difference (p<0.001). Conclusion: Platelet morphology played an important role in thrombosis and this fact could be used therapeutically in future.
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Sharma et al. (2016) studied this question.
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