Why the study?
There is controversy regarding serum vaspin concentrations in CAD, prompting evaluation of serum vaspin levels in relation to CAD severity.
Are serum vaspin levels associated with the presence and severity of coronary artery disease?
Are serum vaspin levels associated with the presence and severity of coronary artery disease?
Decreased serum vaspin levels are associated with the presence and severity of coronary artery disease.
Hypothesis-generating for vaspin as CAD biomarker; does not yet support routine use or practice change.
ObjectiveThe objective of this study was to evaluate serum visceral adipose tissue-derived serpin (vaspin) level with the severity of coronary artery disease (CAD).BackgroundThere is controversy between the researchers on the subject of serum vaspin concentration in CAD.Patients and methodsTwenty control and 68 CAD patients were enrolled in this study. Vaspin was detected by enzyme-linked immunosorbent assay method.ResultsSerum levels of vaspin were significantly low in patients with CAD compared with healthy controls and low vaspin concentrations were correlated with CAD severity.ConclusionsDecreased serum vaspin levels were observed in the existence and severity of CAD in patients assessed by coronary angiography.
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Shorbagy et al. (2021) studied this question.
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