Why the study?
Does quinidine modify vagus inhibition of the heart in subjects with carotid sinus reflex-induced cardiac standstill?
Population
6 human subjects in whom a prolonged cardiac standstill could be consistently induced by pressure on the…
Design
Case_series
Authors
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Does not support clinical quinidine use for vagal effects; leaves open mechanistic questions for controlled study.
Does quinidine modify vagus inhibition of the heart in subjects with carotid sinus reflex-induced cardiac standstill?
This early physiological study aimed to investigate how quinidine modifies vagal inhibition of the sinus node in humans using the carotid sinus reflex.
M. H. Nathanson (1934) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: