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January 1, 2024The Egyptian Journal of Hospital MedicineOpen Access

Association of Mean Platelet Volume with Angiographic Thrombus Burden and Short-term Outcome in Patients with ST-segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention

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Why the study?

Mean platelet volume indicates platelet reactivity and could serve as a biomarker of risk and prognosis in STEMI, prompting evaluation of its predictive value for thrombus burden and short-term outcomes.

Does higher mean platelet volume on admission predict higher angiographic thrombus burden and worse short-term outcomes in patients with STEMI undergoing primary PCI?

Comparison

MPV measured on admission across thrombus burden and outcome categories

Follow-up

3 to 6 months

Discussion

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Member takes

Overview

MPV may identify higher-risk STEMI patients; leaves open whether it adds value to existing risk models.

Structured PICO

Does higher mean platelet volume on admission predict higher angiographic thrombus burden and worse short-term outcomes in patients with STEMI undergoing primary PCI?

P
Population
72 patients with acute ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PPCI), mean age 53.22, 62 males.
I
Intervention
High Mean Platelet Volume (MPV) measured on admission
C
Comparator
Low Mean Platelet Volume (MPV)
O
Outcome
Angiographic thrombus burden, post-interventional TIMI flow grade, myocardial blush grade (MBG), and a primary composite endpoint at 3 to 6 months follow-upcomposite

Higher mean platelet volume on admission in STEMI patients undergoing primary PCI is associated with greater angiographic thrombus burden, worse myocardial perfusion, and poorer short-term clinical outcomes.

Cite This Study

A 2024 study studied this question.

synapsesocial.com/papers/6a880e05ecbb6f2effa53244https://doi.org/10.21608/ejhm.2024.339914
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