Key result
Admission MPV > 9.75 predicts large intracoronary thrombus burden during primary PCI for STEMI.
Why the study?
To assess the association of mean platelet volume as a biomarker for angiographic thrombus burden in patients with STEMI undergoing PPCI.
Does mean platelet volume on admission predict angiographic thrombus burden in patients with STEMI undergoing primary PCI?
Population
125 acute STEMI patients treated with PPCI at El-Mokatem health insurance hospital
Comparison
High MPV vs low MPV (or large vs small thrombus burden)
Design
Observational study
Authors
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MPV may aid thrombus risk stratification in STEMI; hypothesis-generating and requires prospective validation before clinical use.
Observational (n=125)
No
Does mean platelet volume on admission predict angiographic thrombus burden in patients with STEMI undergoing primary PCI?
p-value: p=< 0.001
Higher mean platelet volume on admission is an independent predictor of large angiographic thrombus burden in patients with STEMI undergoing primary PCI.
Mehana et al. (2020) conducted an observational in ST-segment elevation myocardial infarction (STEMI) (n=125). Mean platelet volume (MPV) vs. Low MPV was evaluated on Large intracoronary thrombus burden (LTB) (p=< 0.001). In STEMI patients undergoing primary PCI, an admission mean platelet volume > 9.75 predicted large intracoronary thrombus burden with 83.3% sensitivity and 86.2% specificity.