Key result
Higher admission mean platelet volume linked to ~76% greater 30-day mortality after STEMI primary PCI.
Why the study?
Does high admission mean platelet volume predict impaired myocardial reperfusion and 30-day all-cause mortality in patients with STEMI undergoing primary PCI?
Population
453 patients with STEMI who underwent primary PCI within 12 h of symptoms onset and achieved thrombolysis in…
Comparison
High admission mean platelet volume (MPV) vs Low admission mean platelet volume (MPV)
Design
Cohort
Follow-up
30 days
Authors
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May aid short-term risk stratification in STEMI; leaves open causal role and need for prospective validation.
Observational (n=453)
Does high admission mean platelet volume predict impaired myocardial reperfusion and 30-day all-cause mortality in patients with STEMI undergoing primary PCI?
Effect estimate: HR 1.763 (95% CI 1.009-3.079)
Absolute Event Rate: 6.8% vs 1.5%
p-value: p=0.046
Increased admission mean platelet volume is an independent predictor of impaired myocardial reperfusion and short-term mortality in STEMI patients with successful epicardial reperfusion after primary PCI.
Lai et al. (2015) conducted an observational in ST-segment elevation myocardial infarction (STEMI) (n=453). High admission mean platelet volume (MPV) vs. Low admission MPV was evaluated on All-cause mortality at 30 days (HR 1.763, 95% CI 1.009-3.079, p=0.046). Higher admission mean platelet volume was independently associated with increased 30-day all-cause mortality (HR 1.763; 95% CI 1.009-3.079; P=0.046) in STEMI patients undergoing primary PCI.
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