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September 14, 2015Kardiologia PolskaOpen Access

There was no difference between study groups regarding the primary outcomes (p > 0.05), but the one-year non-fatal re-infarction rate was significantly higher in the highest MPV/Plt ratio group (p = 0.045).

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Why the study?

Does a high admission MPV/Plt ratio predict major adverse cardiac events in STEMI patients undergoing primary PCI?

Population

470 patients with ST-segment elevation myocardial infarction who underwent primary percutaneous coronary…

Comparison

Highest tertile of mean platelet volume to… vs Lower tertiles of MPV/Plt ratio on admission

Design

Cohort

Follow-up

1 year

Authors

İBİsmail BolatÖAÖzgür AkgülHÇHüseyin Altuğ Çakmak

Discussion

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Overview

MPV/Plt ratio associated with re-infarction but not mortality in STEMI; hypothesis-generating and requires prospective validation before clinical use.

Structured PICO

Does a high admission MPV/Plt ratio predict major adverse cardiac events in STEMI patients undergoing primary PCI?

P
Population
470 patients with ST-segment elevation myocardial infarction (STEMI) who underwent primary percutaneous coronary intervention (PCI)
I
Intervention
Highest tertile of mean platelet volume to platelet count (MPV/Plt) ratio on admission (≥ 0.038)
C
Comparator
Lower tertiles of MPV/Plt ratio on admission (≤ 0.029 and 0.029-0.038)
O
Outcome
Composite of cardiovascular (CV) mortality, non-fatal re-infarction, and strokecomposite

Admission MPV/Plt ratio is associated with one-year non-fatal re-infarction but does not predict short- or long-term cardiovascular mortality in STEMI patients undergoing primary PCI.

Cite This Study

Bolat et al. (2015) studied this question.

synapsesocial.com/papers/6a765adea2903f5314475359https://doi.org/10.5603/kp.a2015.0179
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The prognostic value of mean platelet volume to platelet count ratio in older patients with non-ST elevation acute coronary syndrome receiving primary percutaneous coronary intervention: a retrospective study2019 · 3 citations
  2. 2Prognostic implications of mean platelet volume on short- and long-term outcomes among patients with non-ST-segment elevation myocardial infarction treated with percutaneous coronary intervention: A single-center large observational study2016 · 47 citations
  3. 3Predictive Value of Mean Platelet Volume/Platelet Count for Prognosis in Acute Myocardial Infarction2018 · 36 citations
  4. 4Mean Platelet Volume and Its Association With In-Hospital Outcomes in Patients With Acute ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention2024 · 1 citations
  5. 5Mean platelet volume/platelet count ratio as a predictor of long-term mortality after non-ST-elevation myocardial infarction2011 · 125 citations