Key result
A high mean platelet volume to platelet count ratio in older NSTE-ACS patients undergoing primary PCI was associated with higher in-hospital cardiac mortality.
Why the study?
The prognostic value of the mean platelet volume to platelet count ratio for predicting in-hospital and long-term cardiac mortality in older NSTE-ACS patients after primary PCI needed investigation.
Does a high MPV/P ratio predict cardiac mortality in older NSTE-ACS patients receiving primary PCI?
Cohort (n=452)
Does a high MPV/P ratio predict cardiac mortality in older NSTE-ACS patients receiving primary PCI?
A high mean platelet volume to platelet count ratio is an independent predictor of in-hospital and 1-year cardiac mortality in older patients with NSTE-ACS undergoing primary PCI.
Answers are grounded in this paper and cite their sources.
High MPV/P ratio was associated with higher mortality; leaves open its value for risk stratification in older NSTE-ACS pending prospective validation.
BACKGROUND: The aim of this study was to investigate the value of the mean platelet volume to platelet count (MPV/P) ratio for predicting in-hospital and long-term cardiac mortality in older non-ST elevation-acute coronary syndrome (NSTE-ACS) patients after primary percutaneous coronary intervention (PCI). METHODS: We retrospectively reviewed 452 older NSTE-ACS patients who received primary PCI. The patients were divided into two groups based on MPV/P ratios: high MPV/P group (N.=150) defined as a value in the third tertile (>0.056628) and low MPV/P group (N.=302) in the lower two tertiles (≤0.056628). Clinical outcomes included non-fatal reinfarction, heart failure, and cardiac mortality. RESULTS: Multivariate analyses showed that high MPV/P and MPV values were independent predictors of cardiac mortality. The in-hospital cardiac mortality of the high MPV/P group was higher than the low MPV/P group (1.3% vs. 14.7%, P<0.001). The rates of heart failure and cardiac mortality in one year were significantly higher in the high MPV/P group compared to the low MPV/P group (P<0.05). The cut-off value of MPV/P for predicting cardiac death was 0.067107, with a sensitivity of 0.707 and a specificity of 0.868. MPV/P was superior to MPV (z=9.235, P<0.001) for predicting cardiac mortality. CONCLUSIONS: High MPV/P and MPV values are independent predictors of cardiac mortality in older patients with NSTE-ACS receive primary PCI. Moreover, MPV/P is better than MPV for predicting cardiac mortality.
No takes yet. Share an insight, caveat, or question.
Sun et al. (2019) conducted a cohort in Non-ST elevation acute coronary syndrome (NSTE-ACS) (n=452). High MPV/P ratio (>0.056628) vs. Low MPV/P ratio (≤0.056628) was evaluated on In-hospital cardiac mortality (p=<0.001). A high mean platelet volume to platelet count ratio in older NSTE-ACS patients undergoing primary PCI was associated with higher in-hospital cardiac mortality.
Synapse has enriched 10 related papers. Consider them for comparative context: