Why the study?
The prognostic value of the mean platelet volume to platelet count ratio for predicting in-hospital and long-term cardiac mortality in older NSTE-ACS patients after primary PCI needed investigation.
Does a high MPV/P ratio predict cardiac mortality in older NSTE-ACS patients receiving primary PCI?
Population
452 older NSTE-ACS patients who received primary PCI
Comparison
High MPV/P ratio (>0.056628) vs low MPV/P ratio (≤0.056628)
Design
Retrospective study
Follow-up
One year
Key result
A high mean platelet volume to platelet count ratio in older NSTE-ACS patients undergoing primary PCI was associated with higher in-hospital cardiac mortality (14.7% vs. 1.3%, P<0.001).
Authors
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High MPV/P ratio was associated with higher mortality; leaves open its value for risk stratification in older NSTE-ACS pending prospective validation.
Cohort (n=452)
Does a high MPV/P ratio predict cardiac mortality in older NSTE-ACS patients receiving primary PCI?
Absolute Event Rate: 14.7% vs 1.3%
p-value: p=<0.001
A high mean platelet volume to platelet count ratio is an independent predictor of in-hospital and 1-year cardiac mortality in older patients with NSTE-ACS undergoing primary PCI.
Sun et al. (2019) conducted a cohort in Non-ST elevation acute coronary syndrome (NSTE-ACS) (n=452). High MPV/P ratio (>0.056628) vs. Low MPV/P ratio (≤0.056628) was evaluated on In-hospital cardiac mortality (p=<0.001). A high mean platelet volume to platelet count ratio in older NSTE-ACS patients undergoing primary PCI was associated with higher in-hospital cardiac mortality (14.7% vs. 1.3%, P<0.001).