Key result
Higher mean platelet volume (≥8.55 fl) was associated with a significantly higher rate of cardiac death compared to lower MPV in patients undergoing PCI (7.7% vs. 1.9%, p=0.035).
Why the study?
Does higher mean platelet volume predict cardiac death in patients undergoing percutaneous coronary intervention?
Cohort (n=208)
Does higher mean platelet volume predict cardiac death in patients undergoing percutaneous coronary intervention?
Absolute Event Rate: 7.7% vs 1.9%
p-value: p=0.035
Mean platelet volume is a predictive marker for cardiac death after PCI, particularly in patients with acute coronary syndrome, and may be more useful than platelet function testing.
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May support MPV for post-PCI cardiac death risk stratification; leaves open incremental value over standard predictors.
Choi et al. (2013) conducted a cohort in percutaneous coronary intervention (n=208). Higher mean platelet volume (≥8.55 fl) vs. Lower mean platelet volume (<8.55 fl) was evaluated on cardiac death (p=0.035). Higher mean platelet volume (≥8.55 fl) was associated with a significantly higher rate of cardiac death compared to lower MPV in patients undergoing PCI (7.7% vs. 1.9%, p=0.035).
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