Key result
Higher mean platelet volume (>8.20 fL) was associated with a significantly higher rate of cardiac death compared to lower mean platelet volume (9.4% vs. 2.1%, p=0.0026) after PCI.
Why the study?
Does higher mean platelet volume predict cardiac death in patients after percutaneous coronary intervention?
Population
372 patients who underwent percutaneous coronary intervention (PCI) in a Korean cohort
Comparison
Higher mean platelet volume (>8.20 fL) vs Lower mean platelet volume (≤8.20 fL)
Design
Cohort
Follow-up
mean 25.8 months
Authors
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Higher MPV may flag post-PCI patients for closer monitoring; leaves open incremental value over hs-cTnT/NT-proBNP in prospective validation.
Cohort (n=372)
Does higher mean platelet volume predict cardiac death in patients after percutaneous coronary intervention?
Absolute Event Rate: 9.4% vs 2.1%
p-value: p=0.0026
Mean platelet volume >8.20 fL is a predictive biomarker for cardiac death after PCI, with additive value in patients with myocardial injury or heart failure.
Ki et al. (2013) conducted a cohort in Patients who underwent percutaneous coronary intervention (n=372). Higher mean platelet volume (>8.20 fL) vs. Lower mean platelet volume (≤8.20 fL) was evaluated on cardiac death (p=0.0026). Higher mean platelet volume (>8.20 fL) was associated with a significantly higher rate of cardiac death compared to lower mean platelet volume (9.4% vs. 2.1%, p=0.0026) after PCI.
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