Why the study?
Can 40-MHz echocardiography noninvasively image mouse embryonic heart development in utero?
Population
Mouse embryos staged between 8.5 and 13.5 days of gestation, including normal and vascular cell adhesion…
Design
Preclinical
Follow-up
Up to 3 days of embryonic development
Authors
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Enables serial noninvasive phenotyping in mouse embryonic models; leaves open translation to clinical fetal imaging.
Can 40-MHz echocardiography noninvasively image mouse embryonic heart development in utero?
40-MHz echocardiography enables noninvasive, in utero imaging of mouse embryonic heart development and detection of cardiac defects in mutant models.
Srinivasan et al. (1998) studied this question.
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