Key result
EuroSCORE II reliably predicted mortality in octogenarians undergoing off-pump coronary surgery (O/E ratio 0.98) but underestimated mortality for on-pump cases (O/E ratio 1.62).
Why the study?
Octogenarians represent the fastest-growing group in cardiac surgery, but precise risk assessment in this population remains challenging.
Does EuroSCORE II accurately predict mortality in octogenarians undergoing isolated coronary surgery?
Cohort (n=5,771)
Yes
Does EuroSCORE II accurately predict mortality in octogenarians undergoing isolated coronary surgery?
Effect estimate: AUC 0.72 and O/E ratio 0.98 for off-pump; AUC 0.73 and O/E ratio 1.62 for on-pump
EuroSCORE II accurately predicts mortality in octogenarians undergoing off-pump coronary surgery but underestimates risk for on-pump procedures, requiring calibration.
May underestimate on-pump mortality risk in octogenarian CABG; hypothesis-generating for EuroSCORE II recalibration.
Background: Octogenarians constitute the fastest-growing segment within contemporary cardiac surgery, yet precise risk assessment in this age group remains challenging. Aims: This study aimed to evaluate EuroSCORE II reliability in octogenarians undergoing isolated coronary surgery and to create an adjustment formula if necessary. Patients and Methods: All octogenarians who had isolated coronary surgery in Poland from January 2012 to December 2023, recorded in the Polish National Registry of Cardiac Surgical Procedures (KROK registry), were retrospectively assessed. EuroSCORE II’s reliability was measured using the ROC curve area and observed-to-predicted mortality ratio, differentiating on-pump and off-pump cases. A nomogram was developed to enhance predictive accuracy. Results: Among 5771 octogenarians, 2729 (47.3%) underwent on-pump and 3042 (52.7%) underwent off-pump surgery. EuroSCORE II demonstrated reliability in off-pump patients (AUC:0.72, O/E ratio:0.98) but underestimated mortality for on-pump cases (AUC:0.73, O/E ratio:1.62). The lowest predicted mortality group (0.50–1.82%) showed the greatest discrepancies. Calibration was improved by adding a coefficient and creating a nomogram. Conclusions: EuroSCORE II was dependable in predicting outcomes for Polish octogenarians undergoing isolated coronary surgery. Observed mortality following on-pump surgeries was higher than expected, which was corrected by adding a coefficient to the initial EuroSCORE II calculation.
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Hirnle et al. (2024) conducted a cohort in Isolated coronary surgery (n=5,771). EuroSCORE II vs. Observed mortality was evaluated on Mortality prediction reliability (AUC and observed-to-predicted mortality ratio) (AUC 0.72 and O/E ratio 0.98 for off-pump; AUC 0.73 and O/E ratio 1.62 for on-pump). EuroSCORE II reliably predicted mortality in octogenarians undergoing off-pump coronary surgery (O/E ratio 0.98) but underestimated mortality for on-pump cases (O/E ratio 1.62).
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