Key result
Intravenous injection of isosorbide dinitrate significantly reduced central systolic blood pressure from 165.0 mmHg to 142.2 mmHg at 1 minute in patients with isolated systolic hypertension.
Why the study?
Does isosorbide dinitrate intravenous injection reduce central systolic blood pressure and arterial stiffness in patients with isolated systolic hypertension?
Does isosorbide dinitrate intravenous injection reduce central systolic blood pressure and arterial stiffness in patients with isolated systolic hypertension?
Intravenous isosorbide dinitrate selectively lowers central systolic blood pressure and improves arterial stiffness without compromising diastolic blood pressure in patients with isolated systolic hypertension.
Answers are grounded in this paper and cite their sources.
May support acute central BP reduction in isolated systolic hypertension; hypothesis-generating for arterial stiffness effects, pending randomized confirmation.
No abstract yet. The journal hasn't published one we can show.
No takes yet. Share an insight, caveat, or question.
Lee et al. (2007) studied Isolated systolic hypertension (n=30). Isosorbide dinitrate vs. Baseline was evaluated on Central systolic blood pressure at 1 minute (p=<0.001). Intravenous injection of isosorbide dinitrate significantly reduced central systolic blood pressure from 165.0 mmHg to 142.2 mmHg at 1 minute in patients with isolated systolic hypertension.
Synapse has enriched 10 related papers. Consider them for comparative context: