Impacts of Type D Personality and Depression, Alone and in Combination, on Medication Non-Adherence Following Percutaneous Coronary Intervention
Key result
Type D personality increased the risk of medication non-adherence 5.09 times at 3 months, and depression increased it 2.6 times at 1 month, but their combination did not increase risk.
Why the study?
Do Type D personality and depression increase the risk of medication non-adherence in patients following successful PCI?
Population
257 patients who underwent successful percutaneous coronary intervention and were taking 3 or more cardiac…
Comparison
Type D personality and depression vs Patients without Type D personality or depression
Design
Cohort
Follow-up
3 months
Authors
Discussion
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Implication
May support post-PCI psychological screening for non-adherence risk; leaves open causality and intervention effects in prospective trials.
Study Design
Type
Cohort (n=257)
Multicenter
No
Structured PICO
Do Type D personality and depression increase the risk of medication non-adherence in patients following successful PCI?
P
Population
257 PCI patients taking 3 or more cardiac medications, followed for 3 months to assess medication non-adherence.
E
Exposure
Type D personality and depression (alone and in combination)
C
Comparator
Patients without Type D personality or depression
O
Outcome
Medication non-adherence at 1 and 3 months follow-uppatient reported
Main Result
Effect estimate: 5.089 times increased risk
Type D personality and depression independently increase the risk of medication non-adherence at different time points following PCI, highlighting the need for individualized psychological assessments.
Cite This Study
Son et al. (2018) conducted a cohort in percutaneous coronary intervention (PCI) (n=257). Type D personality and depression vs. Patients without Type D personality or depression was evaluated on Medication non-adherence (5.089 times increased risk). Type D personality increased the risk of medication non-adherence 5.09 times at 3 months, and depression increased it 2.6 times at 1 month, but their combination did not increase risk.