Key result
Hypertension was associated with a significantly increased odds of mild cognitive impairment compared to normotension (adjusted OR 1.59), whereas antihypertensive treatment was associated with a reduced risk.
Why the study?
Does the treatment and control of hypertension reduce the risk of mild cognitive impairment in an elderly urban population?
Population
2,065 elderly adults, mean age 71.7, 40.6% male, from an urban community in Beijing, China.
Comparison
Hypertension, and among hypertensive patients… vs Normotensive individuals, untreated hypertensive…
Design
Cross-sectional
Authors
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May support antihypertensive treatment to reduce mild cognitive impairment risk in elderly; leaves open need for randomized confirmation.
Cross-Sectional (n=2,065)
No
Does the treatment and control of hypertension reduce the risk of mild cognitive impairment in an elderly urban population?
Odds Ratio: 1.59 (95% CI 1.07–2.35)
Absolute Event Rate: 16.5% vs 13.1%
p-value: p=0.022
In an elderly Chinese urban population, hypertension is associated with a higher risk of mild cognitive impairment, but pharmacological treatment and control of hypertension are associated with a significantly reduced risk.
Wu et al. (2016) conducted a cross-sectional in Hypertension and Mild Cognitive Impairment (n=2,065). Hypertension vs. Normotension was evaluated on Prevalence of mild cognitive impairment (MCI) (OR 1.59, 95% CI 1.07-2.35, p=0.022). Hypertension was associated with a significantly increased odds of mild cognitive impairment compared to normotension (adjusted OR 1.59), whereas antihypertensive treatment was associated with a reduced risk.
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