Key result
Low adiponectin levels were significantly associated with increased normalized plaque volume (r = -0.16, P = 0.025) and atheroma lipid content (r = -0.19, P = 0.009) in nondiabetic patients.
Why the study?
Are adiponectin levels associated with adverse plaque composition in patients undergoing coronary angiography?
Population
185 patients undergoing coronary angiography and intravascular ultrasound (IVUS)
Design
Cross-sectional
Authors
Loading...
May flag higher-risk plaques on angiography in nondiabetics; leaves open causal and prognostic implications.
Observational (n=185)
Are adiponectin levels associated with adverse plaque composition in patients undergoing coronary angiography?
Effect estimate: r = -0.16
p-value: p=0.025
Low adiponectin levels are associated with increased lipid-rich plaque and pathological intimal thickening in nondiabetic patients, suggesting an antiatherogenic role in early lesion development.
Marso et al. (2008) conducted an observational in Coronary artery disease (n=185). Adiponectin levels was evaluated on Normalized plaque volume and atheroma lipid content (r = -0.16, p=0.025). Low adiponectin levels were significantly associated with increased normalized plaque volume (r = -0.16, P = 0.025) and atheroma lipid content (r = -0.19, P = 0.009) in nondiabetic patients.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: