Population
Isolated reticulum from frog skeletal muscle
Comparison
Temperature changes and caffeine administration vs 20°C temperature and/or absence of caffeine
Design
Preclinical
Authors
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Provides mechanistic insight into rapid cooling contracture in amphibian muscle; leaves open translation to mammalian cardiac reticulum.
Temperature significantly affects calcium uptake and caffeine-induced calcium release in frog skeletal muscle reticulum, providing insight into the mechanism of rapid cooling contracture.
TANIGUCHI et al. (1970) studied this question.
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