Oral Poliomyelitis Vaccine, Lederle — Thirteen Years of Laboratory and Field Investigation

IT is no longer necessary to extol the benefits accruing from the use of attenuated living-virus vaccines, of which smallpox and yellow-fever vaccines are classic examples. In the last fifteen years, as knowledge in the field has increased, over a dozen different live-virus vaccines have been developed and successfully used on a large scale to protect domestic animals. In Russia effective live vaccines against mumps and influenza have recently been reported,1 2 3 4 and work on a live measles vaccine in America5 , 6 holds promise for the near future.Thirteen years ago the firm belief that vaccines containing living attenuated viruses were more . . .