Why the study?
Is the 5q31.1-qter region and specifically the beta2-adrenergic receptor gene linked or associated with essential hypertension?
Population
638 individuals from 212 Polish pedigrees with clustering of essential hypertension
Design
Other
Authors
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Does not support beta2-adrenergic receptor as the major gene for the 5q31.1-5qter linkage; leaves open other candidates in this hypertension locus.
Is the 5q31.1-qter region and specifically the beta2-adrenergic receptor gene linked or associated with essential hypertension?
While the 5q31.1-5qter region is linked to essential hypertension in a Polish population, the beta2-adrenergic receptor gene does not appear to be the major causative gene for this linkage.
Tomaszewski et al. (2002) studied this question.
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