Why the study?
Do polymorphisms in the β2-adrenergic receptor gene influence blood pressure levels and hypertension risk in family cohorts?
Population
Family samples from Rochester, Minn, including 55 pedigrees with ≥1 sibling-pair discordant for systolic…
Comparison
Polymorphisms within the β2-adrenergic receptor… vs Alternative alleles/genotypes at the same…
Design
Cross-sectional
Authors
Loading...
Supports β2-adrenergic polymorphisms as hypertension susceptibility loci; leaves open clinical utility pending prospective validation.
Do polymorphisms in the β2-adrenergic receptor gene influence blood pressure levels and hypertension risk in family cohorts?
Polymorphisms in the β2-adrenergic receptor gene, particularly the Glu27 allele, are identified as susceptibility loci for human hypertension.
Bray et al. (2000) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: