Why the study?
Are polymorphisms in the beta2-adrenergic receptor gene (ADRB2) associated with essential hypertension in a population of Chinese origin?
Population
>800 hypertensive subjects and individuals with low-normal blood pressure of Chinese origin, largely derived…
Comparison
Presence of ADRB2 gene polymorphisms vs Alternative genotypes
Design
Case-control
Authors
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Supports ADRB2 genotyping research in Chinese cohorts; should not yet change hypertension risk assessment or management.
Are polymorphisms in the beta2-adrenergic receptor gene (ADRB2) associated with essential hypertension in a population of Chinese origin?
The Gly16 allele in the beta2-adrenergic receptor gene is identified as a susceptibility allele for essential hypertension in populations of Chinese origin.
K. Ranade (2001) studied this question.
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