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Macrophage plasticity integrates diverse signals in damaged tissues; leaves open targeted immunomodulation in cardiovascular disease pending prospective trials.
Macrophage polarization refers to how macrophages have been activated at a given point in space and time. Polarization is not fixed, as macrophages are sufficiently plastic to integrate multiple signals, such as those from microbes, damaged tissues, and ...Read More
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Goldman et al. (1987) studied this question.
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