Key result
Rotavirus infection in mice routinely resulted in antigenemia and viremia, with infectious virus present in sera and associated with the plasma fraction of blood regardless of age or mouse strain.
Rotavirus infection routinely causes viremia and antigenemia in mouse models, suggesting the virus can access extraintestinal cells via the bloodstream.
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Rotavirus viremia in mice suggests possible systemic spread; hypothesis-generating for human extraintestinal disease and needs clinical confirmation.
Blutt et al. (2006) studied Rotavirus infection. Rotavirus infection was evaluated on Occurrence of rotavirus antigenemia or viremia. Rotavirus infection in mice routinely resulted in antigenemia and viremia, with infectious virus present in sera and associated with the plasma fraction of blood regardless of age or mouse strain.
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