March 19, 2012Catheterization and Cardiovascular Interventions
Acute severe mitral regurgitation following balloon mitral valvotomy: Echocardiographic features, operative findings, and outcome in 50 surgical cases
Key result
Emergency mitral valve replacement within 24 hours for acute severe mitral regurgitation following balloon mitral valvotomy was associated with significantly lower in-hospital mortality (P<0.001).
Why the study?
What are the clinical, echocardiographic, and operative findings, and outcomes in patients undergoing emergency MVR for acute severe MR following BMV?
Population
50 consecutive patients undergoing emergency mitral valve replacement for acute severe mitral regurgitation…
Design
Cohort
Follow-up
In-hospital
Authors
Discussion
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Member takes
Implication
May support early MVR within 24 h for acute severe MR post-BMV; leaves open need for prospective confirmation before practice change.
Study Design
Type
Observational (n=50)
Structured PICO
What are the clinical, echocardiographic, and operative findings, and outcomes in patients undergoing emergency MVR for acute severe MR following BMV?
P
Population
50 consecutive patients undergoing emergency mitral valve replacement for acute severe mitral regurgitation following balloon mitral valvotomy.
E
Exposure
Emergency mitral valve replacement (MVR)
O
Outcome
Echocardiographic and operative findings, clinical profile, and in-hospital mortalityhard clinical
Main Result
p-value: p=<0.001
In patients developing acute severe MR after balloon mitral valvotomy, anterior mitral leaflet tear is the most common etiology, and early surgical intervention (<24 hours) is associated with significantly lower mortality.
Cite This Study
Nanjappa et al. (2012) conducted an observational in Acute severe mitral regurgitation following balloon mitral valvotomy (n=50). Emergency mitral valve replacement <24 hr vs. Emergency mitral valve replacement ≥24 hr was evaluated on In-hospital mortality (p=<0.001). Emergency mitral valve replacement within 24 hours for acute severe mitral regurgitation following balloon mitral valvotomy was associated with significantly lower in-hospital mortality (P<0.001).