IL-6 synergizes with IL-3 and Epo to promote the maturation and process formation of megakaryocytes in vitro, suggesting a mechanism for its thrombopoietic effects in vivo.
No takes yet. Share an insight, caveat, or question.
May guide cytokine strategies for thrombocytopenia; leaves open translation from animal models to human therapy.
Inoue et al. (1993) studied this question.