Plasma and urine ANP concentrations are elevated in diabetic patients with renal complications and correlate with markers of renal tubular damage, suggesting ANP may be an early indicator of fluid homeostasis disturbance in diabetic nephropathy.
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May indicate early fluid imbalance in diabetic nephropathy; leaves open prospective validation as biomarker before clinical use.
Suzuki et al. (1988) studied this question.
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