Why the study?
Does poor glycaemic control in diabetes affect plasma atrial natriuretic factor and plasma renin activity?
Does poor glycaemic control in diabetes affect plasma atrial natriuretic factor and plasma renin activity?
Poorly controlled diabetes is associated with elevated plasma atrial natriuretic factor and reduced plasma renin activity, likely reflecting a normal response to intravascular volume expansion.
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May reflect volume expansion in poor control; hypothesis-generating and should not change practice without prospective data.
Bell et al. (1989) studied this question.
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