Why the study?
Is the diastatic pressure-volume relationship distinguishable from the end-diastolic pressure-volume relationship in assessing passive left ventricular stiffness?
Population
31 subjects undergoing cardiac catheterization for left ventricular pressures and conductance volumes
Comparison
Measurement of diastatic pressure-volume… vs Measurement of end-diastolic pressure-volume…
Design
Cross-sectional
Authors
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Diastatic stiffness may better reflect passive LV properties than EDPVR; leaves open clinical utility pending prospective validation.
Is the diastatic pressure-volume relationship distinguishable from the end-diastolic pressure-volume relationship in assessing passive left ventricular stiffness?
The diastatic pressure-volume relationship is physiologically distinct from the end-diastolic pressure-volume relationship and may better convey passive left ventricular stiffness as it is not coupled to a contracted atrium.
Zhang et al. (2008) studied this question.
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