Why the study?
Does propofol compared to etomidate at varying injection speeds affect induction time and hemodynamics in female patients undergoing anaesthesia?
Population
n=180 female patients requiring induction of anaesthesia, premedicated with temazepam 20 mg
Comparison
Propofol 2.5 mg/kg injected over 20, 40 or 80… vs Etomidate 0.3 mg/kg injected over 20, 40 or 80…
Design
Other
Authors
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Faster injection may shorten induction for both agents; leaves open optimal selection pending randomized hemodynamic trials.
Does propofol compared to etomidate at varying injection speeds affect induction time and hemodynamics in female patients undergoing anaesthesia?
Increasing the speed of injection reduces induction time for both propofol and etomidate, but etomidate provides greater hemodynamic stability while propofol causes more apnoea.
Gillies et al. (1989) studied this question.
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