Why the study?
Does chronic social stress alter blood pressure and mesenteric artery reactivity differently in SHR/y compared to WKY male rats?
Population
Male rats with the spontaneously hypertensive rat Y chromosome and Wistar-Kyoto autosomes and male rats with…
Comparison
Chronic social stress induced by housing in… vs Control housing (10 males)
Design
Preclinical
Authors
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Should not alter hypertension management; leaves open gene-stress interactions in vascular reactivity for human studies.
Does chronic social stress alter blood pressure and mesenteric artery reactivity differently in SHR/y compared to WKY male rats?
Chronic social stress elevates sympathetic nervous system activity, testosterone, and systolic blood pressure, and increases mesenteric artery myogenic reactivity in genetically susceptible SHR/y male rats.
Toot et al. (2010) studied this question.
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