Why the study?
Does vagal afferent activation alter glutamate release in the parabrachial nucleus and affect cardiac baroreflex function in anesthetized male rats?
Population
Anesthetized male rats
Comparison
Vagal afferent activation vs Prestimulated levels; sodium nitroprusside…
Design
Preclinical
Follow-up
2 hours poststimulation
Authors
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May shift baroreflex threshold after vagal stimulation in rats; hypothesis-generating for parabrachial mechanisms with no clinical translation yet.
Does vagal afferent activation alter glutamate release in the parabrachial nucleus and affect cardiac baroreflex function in anesthetized male rats?
Visceral activation via vagal stimulation alters glutamate release in the parabrachial nucleus and has enduring effects on cardiac baroreflex function in rats.
Saleh et al. (1997) studied this question.
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