Population
Wistar-Kyoto rats (WKY) and spontaneously hypertensive rats (SHR)
Comparison
Myocardial infarction induced by coronary artery… vs Sham operation
Design
Preclinical
Follow-up
10 weeks
Authors
Loading...
May mediate post-MI transition to failure in hypertensive models; hypothesis-generating for human relevance.
An increase in G(i alpha) protein may mediate the transition from hypertensive cardiac hypertrophy to heart failure following myocardial infarction.
Kouchi et al. (2000) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: