Why the study?
Data were lacking regarding the significance of PaCO2 across different types of pulmonary hypertension classified by the 2022 definitions.
Does hypocapnia correlate with risk stratification and treatment response in patients with pulmonary hypertension?
Does hypocapnia correlate with risk stratification and treatment response in patients with pulmonary hypertension?
Hypocapnia may indicate worse baseline risk but better response to disease-specific therapy in patients with pulmonary arterial hypertension.
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Hypocapnia may mark higher baseline risk yet better NT-proBNP response in PAH; hypothesis-generating and requires prospective validation before clinical use.
Aetou et al. (2023) studied this question.
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